HDAC3 Antibody

APR12334G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR12334G		100 μl / ￥5450

大規(guī)格詢價

2 Images

訂購信息

安諾倫（北京）生物科技有限公司

Tel: 400-965-8633
Tel: 010-56256916
Inquiry@annoron.com

全國授權(quán)代理商

HDAC3 Antibody

品牌	Leading Biology	貨號	APR12334G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HDAC3 antibody.
分子量	48.8kDa
細胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Colocalizes with XBP1 and AKT1 in the cytoplasm (PubMed:25190803).
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	7G6C5
亞型	IgG2a
基因ID	8841
UniProt ID	O15379
功能	Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys- 27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation (PubMed:21444723, PubMed:23911289). Contributes, together with XBP1 isoform 1, to the activation of NFE2L2-mediated HMOX1 transcription factor gene expression in a PI(3)K/mTORC2/Akt-dependent signaling pathway leading to endothelial cell (EC) survival under disturbed flow/oxidative stress (PubMed:25190803).
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, ICC, E
稀釋方法	WB~~1/500 - 1/2000 IF~~1/200 - 1/1000
別名	Histone deacetylase 3, HD3, 3.5.1.98, RPD3-2, SMAP45, HDAC3
圖像	Figure 1: Western blot analysis using HDAC3 mouse mAb against Hela (1), NIH/3T3 (2), C6 (3) and COS (4) cell lysate. Figure 2: Confocal immunofluorescence analysis of Hela cells using HDAC3 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin.
說明書	Product Datasheet Protocol
數(shù)量

加入購物車詢價

上一產(chǎn)品：NCOR1 Antibody 下一產(chǎn)品：CD20 / MS4A1 (B-Cell Marker) Antibody - Culture Supernatant

熱銷產(chǎn)品

產(chǎn)品添加成功！

購物車已有 0 件產(chǎn)品

繼續(xù)訂購查看訂購單

加入詢價單成功！

詢價單已有 0 件產(chǎn)品

繼續(xù)詢價查看詢價單

選擇	品牌	貨號	產(chǎn)品名稱	規(guī)格	分類	研究領(lǐng)域	說明書	數(shù)量	目錄價
1	Leading Biology	APG01369G	VEGF (Vascular Endothelial Growth Factor) Antibody - Without BSA and Azide	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價
2	Leading Biology	AMM07627G	RIN2 Antibody (monoclonal) (M01)	100 μg	Monoclonal Antibodies				￥4950.00	訂購詢價
3	Leading Biology	APR15980G	FGG Antibody	100 μl	Monoclonal Antibodies				￥5450.00	訂購詢價
4	Leading Biology	AMM05161G	GOB5 / CLCA1 Antibody (clone 1C4)	50 μg	Monoclonal Antibodies				￥5450.00	訂購詢價
5	Leading Biology	APR17667G	ORAI1 Antibody [3F6H5]	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價
6	Leading Biology	APR11118G	HIV-1 p24 Antibody [7F4] (biotin)	0.1 mg	Monoclonal Antibodies				￥6950.00	訂購詢價

最新加入的商品

最新加入的商品

全部產(chǎn)品分類