全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APG02405G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Caspase-4 antibody (Clone D44).
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分子量 |
43262 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane. Mitochondrion
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Caspase-4
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克隆號(hào) |
D44
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亞型 |
Mouse IgG1
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通用名 |
ICH2
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基因ID |
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UniProt ID |
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功能 |
Involved in the activation cascade of caspases responsible for apoptosis execution. Involved in ER-stress induced apoptosis. Cleaves caspase-1.
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總結(jié) |
The caspase family of cysteine proteases play a key role in apoptosis. Like other caspases in the family, caspase-4 is also synthesized as inactive pro-enzyme that is processed in cells by self-proteolysis and/or cleavage by another upstream protease. The processed form of caspase-4 consists of large and small subunits which associate to form an active enzyme. Caspase-4 has been implicated involving in Fas-mediated apoptosis.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB
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別名 |
CASP-4, ICH-2 protease, TX protease, ICH2
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說明書 |
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數(shù)量 |
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