品牌 |
Leading Biology | 貨號(hào) |
APR13049G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Rab5a antibody.
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分子量 |
23.7kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome Cytoplasmic vesicle. Cell projection, ruffle. Membrane. Cytoplasm, cytosol. Note=Enriched in stage I melanosomes. Alternates between membrane-bound and cytosolic forms
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
2E8B11
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亞型 |
IgG1
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通用名 |
RAB5
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基因ID |
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UniProt ID |
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功能 |
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, ICC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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別名 |
Ras-related protein Rab-5A, RAB5A, RAB5
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圖像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 2:Western blot analysis using Rab5a mAb against human Rab5a (AA: 1-215) recombinant protein. (Expected MW is 49.5 kDa) Figure 3:Western blot analysis using Rab5a mAb against HEK293 (1) and Rab5a (AA: 1-215)-hIgGFc transfected HEK293 (2) cell lysate. |
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說明書 |
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數(shù)量 |
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