全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
APR15101G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality B2M antibody.
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分子量 |
13.7kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Note=Detected in serum and urine
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
3G5H8
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亞型 |
IgG2a
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基因ID |
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UniProt ID |
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功能 |
Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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總結(jié) |
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. ;
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
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別名 |
Beta-2-microglobulin, Beta-2-microglobulin form pI 5.3, B2M
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圖像 |
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說明書 |
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數(shù)量 |
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