全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR14754G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ABCB1 antibody.
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分子量 |
141.5kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
6G11F8
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亞型 |
IgG1
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通用名 |
MDR1, PGY1
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基因ID |
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UniProt ID |
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功能 |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
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總結(jié) |
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ;
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
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別名 |
Multidrug resistance protein 1, 3.6.3.44, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243, ABCB1, MDR1, PGY1
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圖像 |
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說明書 |
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數(shù)量 |
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