品牌 |
Leading Biology |
貨號 |
APR10208G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOX10 antibody.
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分子量 |
49.9kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
2E7B5
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia (By similarity).
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總結(jié) |
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. ;
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
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別名 |
Transcription factor SOX-10, SOX10
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圖像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Figure 1: Western blot analysis using SOX10 mAb against human SOX10 recombinant protein. (Expected MW is 31.7 kDa)
Figure 2: Western blot analysis using SOX10 mAb against HEK293 (1) and SOX10 (AA: 147-252)-hIgGFc transfected HEK293 (2) cell lysate.
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說明書 |
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數(shù)量 |
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