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IGFBP7 Antibody

貨號 貨期 規(guī)格 / 價格 詢價
APR16807G 100 μl / ¥5450

IGFBP7 Antibody

品牌

Leading Biology

貨號

APR16807G

產(chǎn)品分類

Monoclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IGFBP7 antibody.

分子量

29.1kDa

細胞定位

Antigen Cellular Localization: Secreted.

宿主

Mouse

種屬反應性

Human

克隆號

1D9E7

亞型

IgG1

通用名

MAC25, PSF

基因ID

UniProt ID

功能

Binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

總結

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ; ; ;

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, IHC, E

稀釋方法

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000

別名

Insulin-like growth factor-binding protein 7, IBP-7, IGF-binding protein 7, IGFBP-7, IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, Prostacyclin-stimulating factor, Tumor-derived adhesion factor, TAF, IGFBP7, MAC25, PSF

圖像

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using IGFBP7 mAb against human IGFBP7 recombinant protein. (Expected MW is 36 kDa)

Figure 2: Western blot analysis using IGFBP7 mAb against HEK293 (1) and IGFBP7 (AA: 52-156)-hIgGFc transfected HEK293 (2) cell lysate.

說明書

數(shù)量

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