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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > MEF2C Antibody

MEF2C Antibody

貨號 貨期 規(guī)格 / 價格 詢價
AMM06359G 100 μl / ¥5450

MEF2C Antibody

品牌

Leading Biology

貨號

AMM06359G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MEF2C antibody.

分子量

51.2kDa

細胞定位

Antigen Cellular Localization: Nucleus.

宿主

Mouse

種屬反應(yīng)性

Human, Mouse

克隆號

6H2G2

亞型

IgG1

基因ID

UniProt ID

功能

Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle- specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture (By similarity). Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC, FC, E

稀釋方法

E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000

別名

Myocyte-specific enhancer factor 2C, MEF2C

圖像

Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Figure 1: Western blot analysis using MEF2C mAb against human MEF2C recombinant protein. (Expected MW is 40 kDa)

Figure 2: Western blot analysis using MEF2C mAb against HEK293 (1) and MEF2C (AA: 1-125)-hIgGFc transfected HEK293 (2) cell lysate.

說明書

數(shù)量

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