KEAP1 Antibody

AMM06185G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06185G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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KEAP1 Antibody

品牌	Leading Biology	貨號(hào)	AMM06185G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KEAP1 antibody.
分子量	69.7kDa
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	7G4B10
亞型	IgG1
通用名	INRF2, KIAA0132, KLHL19
基因ID	9817
UniProt ID	Q14145
功能	Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, FC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000
別名	Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19
圖像	Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using KEAP1 mAb against human KEAP1 recombinant protein. (Expected MW is 52.7 kDa) Figure 2: Flow cytometric analysis of HeLa cells using KEAP1 mouse mAb (green) and negative control (red).
說(shuō)明書	Product Datasheet Protocol
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