品牌 |
Leading Biology | 貨號 |
APR12328G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HAS2 antibody.
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分子量 |
63.5kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號 |
4.00E+07
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction and it is particularly responsible for the synthesis of high molecular mass hyaluronan. Required for the transition of endocardial cushion cells into mesenchymal cells, a process crucial for heart development. May also play a role in vasculogenesis. High molecular mass hyaluronan also play a role in early contact inhibition a process which stops cell growth when cells come into contact with each other or the extracellular matrix (By similarity).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, ICC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
IF~~1/100 - 1/500
IHC~~1/200 - 1/1000
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別名 |
Hyaluronan synthase 2, 2.4.1.212, Hyaluronate synthase 2, Hyaluronic acid synthase 2, HA synthase 2, HAS2
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圖像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using HAS2 mAb against human HAS2 recombinant protein. (Expected MW is 37.5 kDa) Figure 2: Western blot analysis using HAS2 mouse mAb against NTERA-2 (1), HEK293 (2) cell lysate. |
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說明書 |
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數(shù)量 |
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