SRY Antibody

APR13546G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR13546G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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SRY Antibody

品牌	Leading Biology	貨號(hào)	APR13546G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SRY antibody.
分子量	23.9kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus speckle. Cytoplasm. Note=Colocalizes with SOX6 in speckles. Colocalizes with CAML in the nucleus Colocalizes in the nucleus with ZNF208 isoform KRAB-O and tyrosine hydroxylase (TH) (By similarity).
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	1G4
亞型	IgG1
通用名	TDF
基因ID	6736
UniProt ID	Q05066
功能	Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, FC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 FC~~1/200 - 1/400 IHC~~1/200 - 1/1000
別名	Sex-determining region Y protein, Testis-determining factor, SRY, TDF
圖像	Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using SRY mAb against human SRY recombinant protein. (Expected MW is 49.4 kDa) Figure 2: Western blot analysis using SRY mouse mAb against NTERA-2 (1) cell lysate.
說(shuō)明書	Product Datasheet Protocol
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