品牌 |
Leading Biology | 貨號(hào) |
APR11754G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DLL4 antibody.
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分子量 |
74.6kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
4A11
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亞型 |
4A11F8 IgG2b/4A11G2 IgG1
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基因ID |
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UniProt ID |
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功能 |
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
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別名 |
Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
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圖像 |
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng); Figure 1: Western blot analysis using DLL4 mAb against human DLL4 (AA: 313-439) recombinant protein. (Expected MW is 39.2 kDa) Figure 2: Western blot analysis using DLL4 mAb against HEK293 (1) and DLL4 (AA: 313-439)-hIgGFc transfected HEK293 (2) cell lysate. |
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說(shuō)明書(shū) |
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數(shù)量 |
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