GRK2 Antibody

AMM05215G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM05215G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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GRK2 Antibody

品牌	Leading Biology	貨號	AMM05215G
產品分類	Monoclonal Antibodies	研究領域
產品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRK2 antibody.
分子量	80kDa
細胞定位	Antigen Cellular Localization: Cytoplasm {ECO:0000250\|UniProtKB:P21146}. Cell membrane {ECO:0000250\|UniProtKB:P21146}
宿主	Mouse
種屬反應性	Human, Mouse, Rat, Monkey
克隆號	3F8
亞型	IgG1
通用名	BARK, BARK1, GRK2
基因ID	156
UniProt ID	P25098
功能	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC, ICC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/500 - 1/2000 IF~~1/200 - 1/1000
別名	Beta-adrenergic receptor kinase 1, Beta-ARK-1, 2.7.11.15, G-protein coupled receptor kinase 2, ADRBK1, BARK, BARK1, GRK2
圖像	Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); Figure 1: Western blot analysis using GRK2 mouse mAb against Hela (1), Jurkat (2), MOLT4 (3), RAJI (4), THP-1 (5), L1210 (6), Cos7 (7), PC-12 (8), and NIH/3T3 (9) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues (left) and cervical cancer tissues (right) using GRK2 mouse mAb with DAB staining.
說明書	Product Datasheet Protocol
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