p63α Antibody

APR08909G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR08909G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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p63α Antibody

品牌	Leading Biology	貨號(hào)	APR08909G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality p63α antibody.
分子量	51kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus
宿主	Mouse
種屬反應(yīng)性	Human, Mouse, Rat, Monkey
克隆號(hào)	4.00E+05
亞型	IgG1
通用名	KET, P63, P73H, P73L, TP73L
基因ID	8626
UniProt ID	Q9H3D4
功能	Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/500 - 1/2000
別名	Tumor protein 63, p63, Chronic ulcerative stomatitis protein, CUSP, Keratinocyte transcription factor KET, Transformation-related protein 63, TP63, Tumor protein p73-like, p73L, p40, p51, TP63, KET, P63, P73H, P73L, TP73L
圖像	Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); Figure 1: Western blot analysis using p63α mouse mAb against A431 (1), Hela (2), Jurkat (3), THP-1 (4), NIH/3T3 (5), Cos7 (6) and PC-12 (7) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded ovarian cancer (left) and lung cancer (right) using p63α mouse mAb with DAB staining.
說(shuō)明書	Product Datasheet Protocol
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