SNAI1 Antibody

APR10188G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR10188G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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SNAI1 Antibody

品牌	Leading Biology	貨號(hào)	APR10188G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SNAI1 antibody.
分子量	29kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus. Cytoplasm. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs
宿主	Mouse
種屬反應(yīng)性	Human
克隆號(hào)	6D2
亞型	IgG1
通用名	SNAH
基因ID	6615
UniProt ID	O95863
功能	Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up- regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	E~~1/10000 WB~~1/500 - 1/2000
別名	Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna, SNAI1, SNAH
圖像	Red: Control Antigen (100ng); Purple: Antigen (10ng); Green: Antigen (50ng); Blue: Antigen (100ng); Figure 1: Western blot analysis using SNAI1 mAb against human SNAI1 (AA: 2-264) recombinant protein. (Expected MW is 31.3 kDa) Figure 2: Western blot analysis using SNAI1 mouse mAb against NTERA-2 cell lysate.
說(shuō)明書(shū)	Product Datasheet Protocol
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