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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > APAF1 / APAF-1 Antibody (aa1-464, clone 2E12, Low Endotoxin)品牌 |
Leading Biology | 貨號(hào) |
APG01902G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APAF1 / APAF-1 antibody (aa1-464, clone 2E12, Low Endotoxin).
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分子量 |
141840 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rat
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.
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克隆號(hào) |
2.00E+12
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亞型 |
IgG2a,k
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通用名 |
KIAA0413
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基因ID |
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UniProt ID |
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功能 |
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
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總結(jié) |
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, ICC, E, IP
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稀釋方法 |
IHC-P (10 μg/ml), IP (1:1000 - 1:2000), IP (1:1000 - 1:2000), WB (1:1000 - 1:2000),
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別名 |
APAF1, APAF-1, CED4, KIAA0413
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圖像 |
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說(shuō)明書(shū) |
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數(shù)量 |
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