APAF1 / APAF-1 Antibody (aa1-464, clone 2E12, Low Endotoxin)

APG01902G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG01902G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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APAF1 / APAF-1 Antibody (aa1-464, clone 2E12, Low Endotoxin)

品牌	Leading Biology	貨號(hào)	APG01902G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality APAF1 / APAF-1 antibody (aa1-464, clone 2E12, Low Endotoxin).
分子量	141840 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm.
宿主	Rat
種屬反應(yīng)性	Human
靶點(diǎn)	Recognizes the CARD domain of human Apaf-1. Does not cross-react with mouse or rat Apaf-1.
克隆號(hào)	2.00E+12
亞型	IgG2a,k
通用名	KIAA0413
基因ID	317
UniProt ID	O14727
功能	Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
總結(jié)	Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
形式	Liquid
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, ICC, E, IP
稀釋方法	IHC-P (10 μg/ml), IP (1:1000 - 1:2000), IP (1:1000 - 1:2000), WB (1:1000 - 1:2000),
別名	APAF1, APAF-1, CED4, KIAA0413
圖像	Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Western blot analysis using anti-Apaf-1 (human), MAb (2E12) on several human cell lines and one...
說(shuō)明書(shū)	Product Datasheet Protocol
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