品牌 |
Leading Biology |
貨號(hào) |
APR15433G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CHTOP / FOP antibody (C-Terminus, clone KT64).
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分子量 |
26397 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus speckle. Note=Mostly associated with facultative heterochromatin (By similarity). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur.
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宿主 |
Rat
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種屬反應(yīng)性 |
Human, Mouse
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靶點(diǎn) |
Mouse CHTOP / FOP
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克隆號(hào) |
KT64
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亞型 |
IgG2a
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通用名 |
C1orf77, FOP
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基因ID |
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UniProt ID |
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功能 |
Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
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總結(jié) |
Plays an important role in the ligand-dependent activation of estrogen receptor target genes. May play a role in the silencing of fetal globin genes. Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, ICC, IP
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稀釋方法 |
ICC (1:100), IHC-P (10 μg/ml), WB (1:1000),
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別名 |
CHTOP, C1orf77, Chromatin target of PRMT1, DKFZP547E1010, FOP, Friend of PRMT1 protein, Pp7704, SRAG, SRAG-3, SRAG-5, FL-SRAG, RP1-178F15.2
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圖像 |
Anti-CHTOP / FOP antibody IHC staining of human breast.
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說(shuō)明書(shū) |
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數(shù)量 |
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