全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR11891G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FAC1 / BPTF antibody (clone 2F10).
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分子量 |
338kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點 |
Human FAC1 / BPTF
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克隆號 |
2F10
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通用名 |
FAC1, FALZ
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基因ID |
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UniProt ID |
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功能 |
Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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總結(jié) |
Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
ELISA (1:10000), IHC-P (1:50), WB (1:500-1:2000)
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別名 |
Nucleosome-remodeling factor subunit BPTF, Bromodomain and PHD finger-containing transcription factor, Fetal Alz-50 clone 1 protein, Fetal Alzheimer antigen, BPTF, FAC1, FALZ
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圖像 |
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說明書 |
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數(shù)量 |
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