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Monoclonal Antibodies >
SERPINA1 / Alpha 1 Antitrypsin Antibody (clone 5B12)品牌 |
Leading Biology | 貨號 |
AMR09878G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SERPINA1 / Alpha 1 Antitrypsin antibody (clone 5B12).
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分子量 |
47kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Monkey, Dog
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靶點(diǎn) |
Human SERPINA1 / Alpha 1 Antitrypsin
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克隆號 |
5B12
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通用名 |
AAT, PI
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基因ID |
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UniProt ID |
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功能 |
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
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總結(jié) |
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, IP
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稀釋方法 |
IHC-P (10 μg/ml), WB (1:500-1:1000),
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別名 |
Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI
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圖像 |
Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human liver. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINA1... Western blot of extracts (35 ug) from 9 different cell lines by using anti-SERPINA1 monoclonal... |
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說明書 |
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數(shù)量 |
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