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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > SERPINA1 / Alpha 1 Antitrypsin Antibody (clone 5B12)

SERPINA1 / Alpha 1 Antitrypsin Antibody (clone 5B12)

貨號 貨期 規(guī)格 / 價格 詢價
AMR09878G 50 μl / ¥4950

SERPINA1 / Alpha 1 Antitrypsin Antibody (clone 5B12)

品牌

Leading Biology

貨號

AMR09878G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SERPINA1 / Alpha 1 Antitrypsin antibody (clone 5B12).

分子量

47kDa

細(xì)胞定位

Antigen Cellular Localization: Secreted. Endoplasmic reticulum. Note=The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum

宿主

Mouse

種屬反應(yīng)性

Human, Monkey, Dog

靶點(diǎn)

Human SERPINA1 / Alpha 1 Antitrypsin

克隆號

5B12

通用名

AAT, PI

基因ID

UniProt ID

功能

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

總結(jié)

Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IP

稀釋方法

IHC-P (10 μg/ml), WB (1:500-1:1000),

別名

Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, Short peptide from AAT, SPAAT, SERPINA1, AAT, PI

圖像

Anti-SERPINA1 / Alpha 1 Antitrypsin antibody IHC staining of human liver.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINA1...

Western blot of extracts (35 ug) from 9 different cell lines by using anti-SERPINA1 monoclonal...

說明書

數(shù)量

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