MDM4 / MDMX Antibody (clone 4G5)

APR08403G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR08403G		50 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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MDM4 / MDMX Antibody (clone 4G5)

品牌	Leading Biology	貨號(hào)	APR08403G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MDM4 / MDMX antibody (clone 4G5).
分子量	55kDa
細(xì)胞定位	Antigen Cellular Localization: Nucleus.
宿主	Mouse
種屬反應(yīng)性	Human
靶點(diǎn)	Human MDM4 / MDMX
克隆號(hào)	4G5
通用名	MDMX
基因ID	4194
UniProt ID	O15151
功能	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
總結(jié)	Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IF
稀釋方法	IF (1:100), IHC-P (10 μg/ml), WB (1:2000)
別名	Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4, MDM4, MDMX
圖像	HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MDM4... Anti-MDM4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently... Anti-MDM4 / MDMX antibody IHC staining of human tonsil.
說(shuō)明書	Product Datasheet Protocol
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