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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > PSAP / Prosaposin Antibody (clone 4D5F4)

PSAP / Prosaposin Antibody (clone 4D5F4)

貨號 貨期 規(guī)格 / 價格 詢價
AMR09570G 50 μg / ¥4950

PSAP / Prosaposin Antibody (clone 4D5F4)

品牌

Leading Biology

貨號

AMR09570G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PSAP / Prosaposin antibody (clone 4D5F4).

分子量

58kDa

細胞定位

Antigen Cellular Localization: Lysosome

宿主

Mouse

種屬反應(yīng)性

Human

靶點

Human Prosaposin

克隆號

4D5F4

通用名

GLBA, SAP1

基因ID

UniProt ID

功能

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.

總結(jié)

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, ICC, E, Flo

稀釋方法

ELISA (1:10000), Flo (1:200-1:400), ICC (1:50-1:500), IF (1:500), IHC-P (5 μg/ml), WB (1:500-1:2000),

別名

Prosaposin, Proactivator polypeptide, Saposin-A, Protein A, Saposin-B-Val, Saposin-B, Cerebroside sulfate activator, CSAct, Dispersin, Sphingolipid activator protein 1, SAP-1, Sulfatide/GM1 activator, Saposin-C, A1 activator, Co-beta-glucosidase, Glucosylceramidase activator, Sphingolipid activator protein 2, SAP-2, Saposin-D, Component C, Protein C, PSAP, GLBA, SAP1

圖像

Immunofluorescence of HepG2 cells using PSAP mouse monoclonal antibody (green).

說明書

數(shù)量

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