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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > FKBP4 / FKBP52 Antibody (clone Hi52C)

FKBP4 / FKBP52 Antibody (clone Hi52C)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR15989G 50 μg / ¥4950

FKBP4 / FKBP52 Antibody (clone Hi52C)

品牌

Leading Biology

貨號(hào)

APR15989G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FKBP4 / FKBP52 antibody (clone Hi52C).

分子量

52kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor

宿主

Mouse

種屬反應(yīng)性

Human, Mouse, Rat, Hamster, Dog

靶點(diǎn)

Detects an ~52 kD protein representing FKBP52 in HeLa cell lysate. Also detects FKBP52 in whole tissue extracts from rat kidney and rat and mouse testes. Heavy chain migrates close to FKBP52 on SDS-PAGE.

克隆號(hào)

Hi52C

通用名

FKBP52

基因ID

UniProt ID

功能

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

總結(jié)

Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, IF, IP

稀釋方法

IHC-P (10 μg/ml), WB (1:2000),

別名

Peptidyl-prolyl cis-trans isomerase FKBP4, PPIase FKBP4, 5.2.1.8, 51 kDa FK506-binding protein, FKBP51, 52 kDa FK506-binding protein, 52 kDa FKBP, FKBP-52, 59 kDa immunophilin, p59, FK506-binding protein 4, FKBP-4, FKBP59, HSP-binding immunophilin, HBI, Immunophilin FKBP52, Rotamase, Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed, FKBP4, FKBP52

圖像

Prostate tissue was histologically stained with antibodies specific for FKBP52.

FKBP52 (Hi52C), MCF-7 cells.

Anti-FKBP52 antibody IHC of human prostate.

說(shuō)明書

數(shù)量

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