LAT Antibody (clone LAT.10-17 (10-17))

APR17158G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR17158G		50 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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LAT Antibody (clone LAT.10-17 (10-17))

品牌	Leading Biology	貨號	APR17158G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LAT antibody (clone LAT.10-17 (10-17)).
分子量	28kDa
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type III membrane protein Note=Present in lipid rafts
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	LAT.10-17 (10-17)
基因ID	27040
UniProt ID	O43561
功能	Required for TCR (T-cell antigen receptor)- and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
總結(jié)	Required for TCR (T-cell antigen receptor)- and pre-TCR- mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
形式	Liquid
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, IP
稀釋方法	IHC-P (20 μg/ml)
別名	Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT
圖像	Western Blot of 10^6 normal peripheral human blood cells (lane 1), Jurkat (lane 2), and C57BL/6... Anti-LAT antibody IHC of human thymus. Anti-LAT antibody IHC of human tonsil.
說明書	Product Datasheet Protocol
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