品牌 |
Leading Biology |
貨號 |
APR17069G |
產品分類 |
Monoclonal Antibodies |
研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KRT18 / CK18 / Cytokeratin 18 antibody (clone DC-10).
|
分子量 |
48kDa
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm, perinuclear region. Nucleus, nucleolus
|
宿主 |
Mouse
|
種屬反應性 |
Human
|
靶點 |
Reacts with Cytokeratin 18 (45 kD). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.
|
克隆號 |
DC-10
|
通用名 |
CYK18
|
基因ID |
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UniProt ID |
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功能 |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
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總結 |
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.
|
形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應用 |
WB, IHC-P, ICC, E, IP, Flo
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稀釋方法 |
IHC-P (10 μg/ml), IP (1-2 μg/ml), WB (1-2 μg/ml)
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別名 |
Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
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圖像 |
Anti-KRT18 / Cytokeratin 18 antibody IHC of human colon.
Anti-KRT18 / Cytokeratin 18 antibody IHC of human kidney.
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說明書 |
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數(shù)量 |
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