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Basigin / Emmprin / CD147 Antibody (clone MEM-M6/6, Azide-free)品牌 |
Leading Biology | 貨號 |
APG02201G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Basigin / Emmprin / CD147 antibody (clone MEM-M6/6, Azide-free).
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分子量 |
42kDa
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein Melanosome. Note=Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000250|UniProtKB:P18572, ECO:0000269|PubMed:17081065}
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宿主 |
Mouse
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種屬反應性 |
Human
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靶點 |
Recognizes Ig domain D2 (membrane proximal) of CD147 (Neurothelin), a 50-60 kD type I transmembrane glycoprotein primarily expressed on all leukocytes, red blood cells, platelets and endothelial cells; it is not expressed by resting lymphocytes.
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克隆號 |
MEM-M6/6
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基因ID |
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UniProt ID |
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功能 |
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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總結 |
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, Flo, Func
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稀釋方法 |
Func, IHC-P (10 μg/ml),
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別名 |
Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG
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圖像 |
Anti-CD147 antibody IHC staining of human prostate. |
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說明書 |
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數(shù)量 |
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