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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > YWHAB / 14-3-3 Beta Antibody (aa1-246, clone J2E9)

YWHAB / 14-3-3 Beta Antibody (aa1-246, clone J2E9)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APR13976G 50 μg / ¥4950

YWHAB / 14-3-3 Beta Antibody (aa1-246, clone J2E9)

品牌

Leading Biology

貨號(hào)

APR13976G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YWHAB / 14-3-3 Beta antibody (aa1-246, clone J2E9).

分子量

28kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

宿主

Mouse

種屬反應(yīng)性

Human

克隆號(hào)

J2E9

基因ID

UniProt ID

功能

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.

總結(jié)

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.

形式

Liquid

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, IHC-P, E

稀釋方法

IHC-P (5 μg/ml), WB (1:500-1:1000),

別名

14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein beta/alpha, N-terminally processed, YWHAB

圖像

Anti-14-3-3 Beta antibody IHC of human brain, cortex.

Anti-14-3-3 Beta antibody IHC of human kidney.

Anti-14-3-3 Beta antibody IHC of human thyroid.

說(shuō)明書(shū)

數(shù)量

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