品牌 |
Leading Biology |
貨號(hào) |
APR13423G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SNCA / Alpha-Synuclein antibody (aa1-140, clone 5C2).
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分子量 |
14kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
NAC domain of alpha-synuclein (aa 61-95)
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克隆號(hào) |
5C2
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通用名 |
NACP, PARK1
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基因ID |
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UniProt ID |
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功能 |
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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總結(jié) |
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
IHC-P (10 μg/ml), WB (1:500-1:2000),
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別名 |
Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, SNCA, NACP, PARK1
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圖像 |
The recombinant human synuclein family (a-, beta-and ?-) and a-synuclein domains (1-60, 1-95,...
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說明書 |
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數(shù)量 |
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