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Cytokeratin, pan (Epithelial Marker) Antibody - Purified Ab conjugated to PE品牌 |
Leading Biology | 貨號 |
APR14638G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin, pan (Epithelial Marker) antibody - Purified Ab conjugated to PE .
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分子量 |
67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19)
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宿主 |
Mouse
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種屬反應性 |
Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog
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克隆號 |
SPM115 + SPM116
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亞型 |
Mouse / IgG's
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通用名 |
KRT1B
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基因ID |
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UniProt ID |
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總結 |
Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3, CK4, CK5, CK6, CK8, CK10, CK14, CK15, CK16, and CK19. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. This MAb is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.
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形式 |
Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, IF, FC
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別名 |
Keratin, type II cytoskeletal 1b, Cytokeratin-1B, CK-1B, Keratin-77, K77, Type-II keratin Kb39, KRT77, KRT1B
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圖像 |
Flow Cytometry of human Pan-Cytokeratins on HeLa Cells. Black: Cells alone; Green: Isotype Control; Red: PE-labeled Pan-Cytokeratin Monoclonal Antibody (SPM115 + SPM116). |
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說明書 |
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數(shù)量 |
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