全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR15342G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CD28 antibody [Clone CB28].
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分子量 |
44kDa (monomer); 88kDa (dimer)
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點 |
Recombinant human CD28 protein
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克隆號 |
CB28
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亞型 |
IgG1, kappa
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基因ID |
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UniProt ID |
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功能 |
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
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總結(jié) |
Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
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形式 |
0.5 ml at 200ug/ml; Conjugated to AF488
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
FC
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別名 |
T-cell-specific surface glycoprotein CD28, TP44, CD28, CD28
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說明書 |
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數(shù)量 |
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