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> 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Anti-Human Myeloperoxidase (MPO) Antibody (Clone 12D06)品牌 |
Leading Biology | 貨號 |
APG01893G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Anti-Human Myeloperoxidase (MPO) antibody (Clone 12D06).
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分子量 |
83869 Da
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細胞定位 |
Antigen Cellular Localization:
Lysosome.
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宿主 |
Mou
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種屬反應(yīng)性 |
Human
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靶點 |
MPO
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克隆號 |
12D06
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亞型 |
Mouse IgG1κ
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基因ID |
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UniProt ID |
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功能 |
Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
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總結(jié) |
Myeloperoxidase (MPO) is highly expressed in neutrophils and polymorphonuclear luekocytes. MPO is expressed as a dimer in regular neutrophils with a 140 kDA. The glycosylated form of MPO has a molecular weight of 92 kDa and when undergoes a final glycosylation, MPO forms subunits of 60 kDa and 12 kDa. In recent studies, MPO was shown to be involved in the initiation and progression of cardiovascular disease.
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形式 |
Liquid
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
FC, E
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別名 |
89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain
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說明書 |
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數(shù)量 |
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