品牌 |
Leading Biology | 貨號(hào) |
APR10362G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SUZ12 antibody.
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分子量 |
83.1kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
2C11
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亞型 |
IgG1
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通用名 |
CHET9, JJAZ1, KIAA0160
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基因ID |
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UniProt ID |
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功能 |
Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, ICC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
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別名 |
Polycomb protein SUZ12, Chromatin precipitated E2F target 9 protein, ChET 9 protein, Joined to JAZF1 protein, Suppressor of zeste 12 protein homolog, SUZ12, CHET9, JJAZ1, KIAA0160
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圖像 |
Figure 1: Western blot analysis using SUZ12 mAb against HEK293 (1) and SUZ12(AA: 533-739)-hIgGFc transfected HEK293 (2) cell lysate. Figure 2: Immunofluorescence analysis of U251 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Figure 3: Immunofluorescence analysis of MCF-7 cells using SUZ12 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. |
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說(shuō)明書 |
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數(shù)量 |
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