品牌 |
Leading Biology | 貨號 |
APR15117G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality BCL-2 antibody.
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分子量 |
26kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse
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克隆號 |
8.00E+12
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亞型 |
IgG1
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基因ID |
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UniProt ID |
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功能 |
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, FC, ICC, E
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稀釋方法 |
FC~~1/200 - 1/400
IF~~1/200 - 1/1000
IHC~~1/500 - 1/2000
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別名 |
Apoptosis regulator Bcl-2, BCL2
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圖像 |
Figure 1: Flow cytometric analysis of 3T3L1 cells using BCL-2 mouse mAb (green) and negative control (purple). Figure 2: Immunofluorescence analysis of NIH/3T3 cells using BCL-2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Figure 3: Immunohistochemical analysis of paraffin-embedded colon cancer tissues (left) and human brain tissues (right) using BCL-2 mouse mAb with DAB staining. |
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說明書 |
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數(shù)量 |
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