品牌 |
Leading Biology | 貨號(hào) |
AMR09689G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Rab25 antibody.
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分子量 |
24kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, pseudopodium membrane. Cytoplasmic vesicle. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse
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克隆號(hào) |
3F12
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亞型 |
IgG1
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通用名 |
CATX8
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基因ID |
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UniProt ID |
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功能 |
Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Increases the rates of ovarian and breast cancers progression and aggressiveness by modulating cellular processes such as proliferation, survival and migration of epithelial tumor cells. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity).
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, FC, ICC, E
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稀釋方法 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
FC~~1/200 - 1/400
IF~~1/200 - 1/1000
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別名 |
Ras-related protein Rab-25, CATX-8, RAB25, CATX8
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圖像 |
Figure 1: Western blot analysis using Rab25 mouse mAb against MCF-7 (1), T47D (2) and GC7901 (3) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded esophagus tissues (left) and human lung cancer (right) using Rab25 mouse mAb with DAB staining. Figure 3: Flow cytometric analysis of NIH/3T3 cells using Rab25 mouse mAb (green) and negative control (purple). |
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說(shuō)明書(shū) |
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數(shù)量 |
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