Metadherin Antibody

AMM06386G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM06386G		100 μl / ￥4950

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Metadherin Antibody

品牌	Leading Biology	貨號	AMM06386G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Metadherin antibody.
分子量	64kDa
細(xì)胞定位	Antigen Cellular Localization: Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Cell junction, tight junction. Nucleus, nucleolus. Cytoplasm, perinuclear region. Note=In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes. A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain (By similarity). TNF-alpha causes translocation from the cytoplasm to the nucleus.
宿主	Mouse
種屬反應(yīng)性	Human
克隆號	2F11C3
亞型	IgG1
通用名	AEG1, LYRIC
基因ID	92140
UniProt ID	Q86UE4
功能	Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF- kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
形式	Liquid. In PBS containing 0.02% sodium azide.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, FC, E
稀釋方法	WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 FC~~1/200 - 1/400 ICC~~1:200~~1000 IF~~1:200~1000.
別名	Protein LYRIC, 3D3/LYRIC, Astrocyte elevated gene-1 protein, AEG-1, Lysine-rich CEACAM1 co-isolated protein, Metadherin, Metastasis adhesion protein, MTDH, AEG1, LYRIC
圖像	Figure 1: Western blot analysis using Metadherin mouse mAb against K562 (1), SKBR-3 (2), T47D (3), Hela (4) and MCF-7 (5) cell lysate. Figure 2: Immunohistochemical analysis of paraffin-embedded human Liver tissues using Metadherin mouse mAb Figure 3: Flow cytometric analysis of Hela cells using Metadherin mouse mAb (green) and negative control (purple).
說明書	Product Datasheet Protocol
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