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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > FRK Antibody

FRK Antibody

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM04614G 100 μl / ¥4950

FRK Antibody

品牌

Leading Biology

貨號

AMM04614G

產(chǎn)品分類

Monoclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FRK antibody.

分子量

58kDa

細(xì)胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Predominantly found in the nucleus, with a small fraction found in the cell periphery

宿主

Mouse

種屬反應(yīng)性

Human

克隆號

4.00E+01

亞型

IgG1

通用名

PTK5, RAK

基因ID

UniProt ID

功能

Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.

形式

Liquid. In PBS containing 0.02% sodium azide.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1/500 - 1/2000 IHC~~1:200~~1000 IF~~1:200~1000.

別名

Tyrosine-protein kinase FRK, 2.7.10.2, FYN-related kinase, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, FRK, PTK5, RAK

圖像

Figure 1: Western blot analysis using FRK mouse mAb against K562 cell lysate (1).

Figure 2: Immunohistochemical analysis of paraffin-embedded human normal stomach (A), normal liver (B), normal kidney (C) and rectum cancer tissues (D) using WNT10B mouse mAb with DAB staining.

Figure 3: Confocal immunofluorescence analysis of PANC-1 cells using anti-WNT10B mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Blue: DRAQ5 fluorescent DNA dye.

說明書

數(shù)量

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