UBE3A Antibody (monoclonal) (M01)

AMM05461G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMM05461G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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UBE3A Antibody (monoclonal) (M01)

品牌	Leading Biology	貨號	AMM05461G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE3A antibody (monoclonal) (M01).
分子量	100688 Da
宿主	mouse
種屬反應(yīng)性	Human, Rat
靶點	UBE3A (AAH09271, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號	2F6
亞型	IgG2a Kappa
基因ID	7337
UniProt ID	Q05086
總結(jié)	This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF, E
稀釋方法	WB~~1:500~1000
別名	Ubiquitin-protein ligase E3A, 632-, E6AP ubiquitin-protein ligase, Human papillomavirus E6-associated protein, Oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54, UBE3A, E6AP, EPVE6AP, HPVE6A
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . UBE3A monoclonal antibody (M01), clone 2F6 Western Blot analysis of UBE3A expression in Jurkat ( (Cat AMM05461G ) Immunoperoxidase of monoclonal antibody to UBE3A on formalin-fixed paraffin-embedded human lung. [antibody concentration 3 ug/ml]
說明書	Product Datasheet Protocol
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