TPMT Antibody (monoclonal) (M02)

APR10525G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR10525G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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TPMT Antibody (monoclonal) (M02)

品牌	Leading Biology	貨號(hào)	APR10525G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TPMT antibody (monoclonal) (M02).
分子量	28180 Da
宿主	mouse
種屬反應(yīng)性	Human
靶點(diǎn)	TPMT (AAH05339, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號(hào)	1D4
亞型	IgG1 Kappa
基因ID	7172
UniProt ID	P51580
總結(jié)	This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, E
稀釋方法	WB~~1:500~1000
別名	Thiopurine S-methyltransferase, Thiopurine methyltransferase, TPMT
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (52.69 KDa) . Western Blot analysis of TPMT expression in transfected 293T cell line by TPMT monoclonal antibody (M02), clone 1D4. Lane 1: TPMT transfected lysate(28.2 KDa). Lane 2: Non-transfected lysate. Immunofluorescence of monoclonal antibody to TPMT on HeLa cell. [antibody concentration 10 ug/ml]
說(shuō)明書(shū)	Product Datasheet Protocol
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