品牌 |
Leading Biology | 貨號 |
APR07165G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PSMC4 antibody (monoclonal) (M01).
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分子量 |
47366 Da
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宿主 |
mouse
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種屬反應(yīng)性 |
Human
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靶點 |
PSMC4 (AAH00343, 1 a.a. ~ 418 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號 |
3G8
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亞型 |
IgG2a kappa
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基因ID |
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UniProt ID |
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總結(jié) |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with an orphan member of the nuclear hormone receptor superfamily highly expressed in liver, and with gankyrin, a liver oncoprotein. Two transcript variants encoding different isoforms have been identified.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, E
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稀釋方法 |
WB~~1:500~1000
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別名 |
26S protease regulatory subunit 6B, 26S proteasome AAA-ATPase subunit RPT3, MB67-interacting protein, MIP224, Proteasome 26S subunit ATPase 4, Tat-binding protein 7, TBP-7, PSMC4, MIP224, TBP7
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圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (71.72 KDa) . PSMC4 monoclonal antibody (M01), clone 3G8 Western Blot analysis of PSMC4 expression in HepG2 ( (Cat APR07165G ) Western Blot analysis of PSMC4 expression in transfected 293T cell line by PSMC4 monoclonal antibody (M01), clone 3G8. Lane 1: PSMC4 transfected lysate(47.4 KDa). Lane 2: Non-transfected lysate. |
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說明書 |
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數(shù)量 |
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