PNMA1 Antibody (monoclonal) (M01)

APR12907G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR12907G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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PNMA1 Antibody (monoclonal) (M01)

品牌	Leading Biology	貨號	APR12907G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PNMA1 antibody (monoclonal) (M01).
分子量	39761 Da
宿主	mouse
種屬反應(yīng)性	Human, Mouse
靶點(diǎn)	PNMA1 (NP_006020, 62 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號	4G6
亞型	IgG2a Kappa
基因ID	9240
UniProt ID	Q8ND90
總結(jié)	The PNMA1 gene encodes an antineuronal antibody (anti-Ma) present in patients with paraneoplastic neurologic disorders (Dalmau et al., 1999 [PubMed 10050892]). Some paraneoplastic syndromes affecting the nervous system are associated with antibodies that react with neuronal proteins and the causal tumor (onconeuronal antigens) (summarized by Dalmau et al., 1999 [PubMed 10050892]). Several of these antibodies are markers of specific neurologic syndromes associated with distinct types of cancer. The presence of some antibodies is so specific that disorders previously identified by brain biopsy or at autopsy can be diagnosed serologically. The expression of neuronal proteins by the tumor appears to be a crucial step that breaks the immune tolerance for otherwise normal neuronal proteins. The identity of most onconeuronal antigens was established by probing human cDNA expression libraries with serum containing antineuronal antibodies.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
稀釋方法	WB~~1:500~1000
別名	Paraneoplastic antigen Ma1, 37 kDa neuronal protein, Neuron- and testis-specific protein 1, PNMA1, MA1
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . PNMA1 monoclonal antibody (M01), clone 4G6 Western Blot analysis of PNMA1 expression in IMR-32 ( (Cat APR12907G ) PNMA1 monoclonal antibody (M01), clone 4G6. Western Blot analysis of PNMA1 expression in Raw 264.7 ( (Cat APR12907G )
說明書	Product Datasheet Protocol
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