品牌 |
Leading Biology |
貨號(hào) |
APR14371G |
產(chǎn)品分類(lèi) |
Monoclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PIK3C2B antibody (monoclonal) (M02).
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分子量 |
184768 Da
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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靶點(diǎn) |
PIK3C2B (NP_002637, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號(hào) |
3.00E+06
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亞型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is sensitive to low nanomolar levels of the inhibitor wortmanin. The C2 domain of this protein was shown to bind phospholipids but not Ca2+, which suggests that this enzyme may function in a calcium-independent manner.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IF, E
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稀釋方法 |
WB~~1:500~1000
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別名 |
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, PI3K-C2-beta, PtdIns-3-kinase C2 subunit beta, C2-PI3K, Phosphoinositide 3-kinase-C2-beta, PIK3C2B
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圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (37.84 KDa) .
PIK3C2B monoclonal antibody (M02), clone 3E5 Western Blot analysis of PIK3C2B expression in A-431 ( (Cat APR14371G )
Immunofluorescence of monoclonal antibody to PIK3C2B on A-431 cell. [antibody concentration 10 ug/ml]
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說(shuō)明書(shū) |
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數(shù)量 |
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