品牌 |
Leading Biology | 貨號(hào) |
APR08956G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PCSK1 antibody (monoclonal) (M02).
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分子量 |
84152 Da
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human, Mouse, Rat
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靶點(diǎn) |
PCSK1 (NP_000430, 652 a.a. ~ 753 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號(hào) |
3D2
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亞型 |
IgG3 Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a type I proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. It is also known to cleave proopiomelanocortin, prorenin, proenkephalin, prodynorphin, prosomatostatin and progastrin. Mutations in this gene are thought to cause obesity. This encoded protein is associated with carcinoid tumors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC, IF, E
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稀釋方法 |
WB~~1:500~1000
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別名 |
Neuroendocrine convertase 1, NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1, PCSK1, NEC1
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圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.96 KDa) . PCSK1 monoclonal antibody (M02), clone 3D2 Western Blot analysis of PCSK1 expression in HeLa ( (Cat APR08956G ) PCSK1 monoclonal antibody (M02), clone 3D2. Western Blot analysis of PCSK1 expression in PC-12(Cat APR08956G ) |
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說明書 |
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數(shù)量 |
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