LFNG Antibody (monoclonal) (M01)

AMM06248G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06248G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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LFNG Antibody (monoclonal) (M01)

品牌	Leading Biology	貨號(hào)	AMM06248G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LFNG antibody (monoclonal) (M01).
分子量	41773 Da
宿主	mouse
種屬反應(yīng)性	Human
靶點(diǎn)	LFNG (AAH14851, 1 a.a. ~ 250 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號(hào)	2D10-3C11
亞型	IgG1 kappa
基因ID	3955
UniProt ID	Q8NES3
總結(jié)	This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF, E
稀釋方法	WB~~1:500~1000
別名	Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase, LFNG
圖像	LFNG monoclonal antibody (M01), clone 2D10-3C11 Western Blot analysis of LFNG expression in HL-60 ( Cat L014V1 ). Immunofluorescence of monoclonal antibody to LFNG on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged LFNG is approximately 3ng/ml as a capture antibody.
說明書	Product Datasheet Protocol
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