GIT2 Antibody (monoclonal) (M01)

APR14321G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14321G		100 μg / ￥4950

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GIT2 Antibody (monoclonal) (M01)

品牌	Leading Biology	貨號	APR14321G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GIT2 antibody (monoclonal) (M01).
分子量	84543 Da
宿主	mouse
種屬反應(yīng)性	Human
靶點	GIT2 (AAH01379, 1 a.a. ~ 471 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號	3B5-B9
亞型	IgG2a Kappa
基因ID	9815
UniProt ID	Q14161
總結(jié)	This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined. The various isoforms have functional differences, with respect to ARF GAP activity and to G protein-coupled receptor kinase 2 binding.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, IF
稀釋方法	WB~~1:500~1000
別名	ARF GTPase-activating protein GIT2, ARF GAP GIT2, Cool-interacting tyrosine-phosphorylated protein 2, CAT-2, CAT2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2, GIT2, KIAA0148
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (77.33 KDa) . GIT2 monoclonal antibody (M01), clone 3B5-B9 Western Blot analysis of GIT2 expression in Jurkat ( (Cat APR14321G ) Western Blot analysis of GIT2 expression in transfected 293T cell line by GIT2 monoclonal antibody (M01), clone 3B5-B9. Lane 1: GIT2 transfected lysate(52.6 KDa). Lane 2: Non-transfected lysate.
說明書	Product Datasheet Protocol
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