品牌 |
Leading Biology |
貨號(hào) |
AMM06943G |
產(chǎn)品分類 |
Monoclonal Antibodies |
研究領(lǐng)域 |
|
產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOCK4 antibody (monoclonal) (M03).
|
分子量 |
225206 Da
|
宿主 |
mouse
|
種屬反應(yīng)性 |
Human
|
靶點(diǎn) |
DOCK4 (NP_055520, 1867 a.a. ~ 1966 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
|
克隆號(hào) |
1B3
|
亞型 |
IgG3 Kappa
|
基因ID |
|
UniProt ID |
|
總結(jié) |
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.
|
形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
|
儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
應(yīng)用 |
WB, E
|
稀釋方法 |
WB~~1:500~1000
|
別名 |
Dedicator of cytokinesis protein 4, DOCK4, KIAA0716
|
圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
Detection limit for recombinant GST tagged DOCK4 is approximately 0.3ng/ml as a capture antibody.
|
說明書 |
|
數(shù)量 |
|