品牌 |
Leading Biology | 貨號 |
APG02874G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYP24A1 antibody (monoclonal) (M07).
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分子量 |
58875 Da
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宿主 |
mouse
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種屬反應(yīng)性 |
Human
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靶點 |
CYP24A1 (NP_000773, 415 a.a. ~ 514 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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克隆號 |
1F8
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亞型 |
IgG2a Kappa
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基因ID |
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UniProt ID |
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總結(jié) |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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形式 |
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:500~1000
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別名 |
25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24, CYP24A1, CYP24
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圖像 |
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Western Blot analysis of CYP24A1 expression in transfected 293T cell line by CYP24A1 monoclonal antibody (M07), clone 1F8. Lane 1: CYP24A1 transfected lysate (Predicted MW: 11.11 KDa). Lane 2: Non-transfected lysate. Detection limit for recombinant GST tagged CYP24A1 is approximately 0.1ng/ml as a capture antibody. |
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說明書 |
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數(shù)量 |
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