CTLA4 Antibody (monoclonal) (M08)

APR15621G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR15621G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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CTLA4 Antibody (monoclonal) (M08)

品牌	Leading Biology	貨號(hào)	APR15621G
產(chǎn)品分類(lèi)	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTLA4 antibody (monoclonal) (M08).
分子量	24656 Da
宿主	mouse
種屬反應(yīng)性	Human
靶點(diǎn)	CTLA4 (NP_005205, 36 a.a. ~ 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號(hào)	1F4
亞型	IgG2a Kappa
基因ID	1493
UniProt ID	P16410
總結(jié)	This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:500~1000
別名	Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CTLA4, CD152
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) . Detection limit for recombinant GST tagged CTLA4 is approximately 0.3ng/ml as a capture antibody. Proximity Ligation Analysis of protein-protein interactions between CD86 and CTLA4. HeLa cells were stained with anti-CD86 rabbit purified polyclonal 1:1200 and anti-CTLA4 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
說(shuō)明書(shū)	Product Datasheet Protocol
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