CASP1 Antibody (monoclonal) (M01)

APG02375G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APG02375G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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Tel: 010-56256916
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CASP1 Antibody (monoclonal) (M01)

品牌	Leading Biology	貨號(hào)	APG02375G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CASP1 antibody (monoclonal) (M01).
分子量	45159 Da
宿主	mouse
種屬反應(yīng)性	Human
靶點(diǎn)	CASP1 (AAH62327, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號(hào)	3D2
亞型	IgG2a Kappa
基因ID	834
UniProt ID	P29466
總結(jié)	This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC, E
稀釋方法	WB~~1:500~1000
別名	Caspase-1, CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p20, Caspase-1 subunit p10, CASP1, IL1BC, IL1BCE
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) . Western Blot analysis of CASP1 expression in transfected 293T cell line by CASP1 monoclonal antibody (M01), clone 3D2. Lane 1: CASP1 transfected lysate(35 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to CASP1 on formalin-fixed paraffin-embedded human hepatocellular carcinoma. [antibody concentration 3 ug/ml]
說明書	Product Datasheet Protocol
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