AKT1 Antibody (monoclonal) (M09)

APG01688G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG01688G		100 μg / ￥4950

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安諾倫（北京）生物科技有限公司

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AKT1 Antibody (monoclonal) (M09)

品牌	Leading Biology	貨號	APG01688G
產(chǎn)品分類	Monoclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality AKT1 antibody (monoclonal) (M09).
分子量	55686 Da
宿主	mouse
種屬反應(yīng)性	Human, Mouse, Rat
靶點	AKT1 (AAH00479.1, 1 a.a. ~ 480 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
克隆號	6F11
亞型	IgG2a Lambda
基因ID	207
UniProt ID	P31749
總結(jié)	The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
形式	Clear, colorless solution in phosphate buffered saline, pH 7.2 .
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IF
稀釋方法	WB~~1:500~1000
別名	RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC
圖像	Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (78.54 KDa) . AKT1 monoclonal antibody (M09), clone 6F11. Western Blot analysis of AKT1 expression in PC-12(Cat APG01688G ) AKT1 monoclonal antibody (M09), clone 6F11. Western Blot analysis of AKT1 expression in Raw 264.7(Cat APG01688G )
說明書	Product Datasheet Protocol
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