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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Monoclonal Antibodies > Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide

Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide

貨號 貨期 規(guī)格 / 價格 詢價
APR14531G 100 μg / ¥4950

Cytokeratin 18 (KRT18) Antibody - Without BSA and Azide

品牌

Leading Biology

貨號

APR14531G

產(chǎn)品分類

Monoclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Cytokeratin 18 (KRT18) antibody - Without BSA and Azide.

分子量

45kDa

細胞定位

Antigen Cellular Localization: Cytoplasm, perinuclear region. Nucleus, nucleolus

宿主

Mouse

種屬反應性

Human, Mouse, Rat, Hamster, Pig, Chicken, Goat, Cow, Marmoset, Sheep, Xenopus, Horse, Dog, Cat

克隆號

C-04; same as Ks18.04

亞型

Mouse / IgG1, kappa

通用名

CYK18

基因ID

UniProt ID

功能

Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

總結

This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

形式

Liquid

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

IHC, IF, FC

別名

Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18

圖像

Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with Cytokeratin 18 Monoclonal Antibody (C-04).

說明書

數(shù)量

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