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Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody - Without BSA and Azid品牌 |
Leading Biology | 貨號(hào) |
APR14585G |
產(chǎn)品分類 |
Monoclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) antibody - Without BSA and Azid.
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分子量 |
55kDa
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Mouse
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種屬反應(yīng)性 |
Human
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克隆號(hào) |
KRT7/760
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亞型 |
Mouse / IgG1
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通用名 |
SCL
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基因ID |
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UniProt ID |
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功能 |
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
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總結(jié) |
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
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形式 |
Liquid
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
IHC, IF, FC
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別名 |
Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL
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圖像 |
Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with Cytokeratin 7 Monoclonal Antibody (KRT7/760) Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Cytokeratin 7 Monoclonal Antibody (KRT7/760) Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with Cytokeratin 7 Monoclonal Antibody (KRT7/760) |
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說(shuō)明書 |
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數(shù)量 |
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